Endocrine Abstracts

Introduction: Type 2 diabetes mellitus, has gained a lot of attention in recent years as one of the most important chronic progressive diseases in the world, which slowly crawls towards longevity and which involves many chronic complications, which are dangerous to health and the economy. Sodium-glucose cotransporter-2 (SGLT2) inhibitors represent a category of newly discovered drugs that work by preventing glucose reabsorption in the proximal renal tubules. (SGLT2) Inhibitors...

Introduction: Diabetes mellitus is not just a disease as it is already known, the matter is more complicated, and it is considered as an assembly of metabolic defects with end result of hyperglycemia. verapamil can decrease the expression of thioredoxin-interacting protein (TXNIP), which is recognized as an important factor in pancreatic beta cells. verapamil could enhance beta cell mass and function.Materials and methods: 160 type 2 diabetes mellitus an...

In order for type 2 diabetes to occur, insulin resistance occurs first, which often occurs from an increase in fat deposition in the liver and the pancreas, and with this resistance. It is universally agreed that diabetes diagnosis is by analyzing blood glucose. The ultrasound technology often helps in diagnosis and quick decision-making in the treatment of many diseases. It can tell us about the muscles’ echogenicity.Materials and Methods: 400 pati...

Introduction: Many researchers are linking diabetes with obesity, which has become very prevalent now, but we see large numbers of diabetics with normal weight as we see obese persons, but they are not necessarily diabetics, which calls us seriously to review this matter, taking into account that obesity is a factor in the occurrence of diabetes. Many studies have talked about visceral fat, as well as about the ratio between visceral fat and subcutaneous fat and its role in th...

Objectives: The aim was to show if the combination of topiramate and empagliflozin have the greatest weight decreasing effect in comparison to each drug alone and to control.Design: Observational cohort prospective study 6-month trial.Materials and methods: Observational cohort prospective study with the following of 200 obese patients who were in 4 parallel groups. Had been monitored in a private clinic, each group 50 patient...

GABA from medical nutrition to pancreatic beta-cell regeneration.Introduction: Type 1 diabetes is considered as one of the most widespread chronic diseases in the world, which happens due to autoimmune damage of beta cells in islets of langerhans in the pancreas. It is the most widespread type of diabetes in young age below 18 years(1.2).The beginning or progress of autoimmune cellular injury of pancreatic beta cells could occur through the presence of m...

Introduction: When diabetes mellitus is diagnosed, peripheral neuropathy is present in about 20 % of cases. Vibratory sense is perceived by mechanoreceptors, which have 2 types, Pacinian corpuscles and Meissner corpuscles. Pacinian corpuscles consist of large myelinated A-beta fibers detecting high frequency vibration and deep pressure. There are new methods to evaluate vibration sense and pressure sensation acting on Aβ, and C type fibres. TENS is considered as a non-inv...

Introduction: Hashimoto thyroiditis is the prominent face in thyroid diseases, and it is considered as an autoimmune disorder, in which the immune system develops antibodies against thyroid peroxidase enzyme which has a role in thyroid hormone production. No treatment for hashimoto thyroiditis itself, only patients with low thyroid hormone with high TSH levels require treatment with thyroxin. It is known that about 25 genes converting data regarding selenoproteins are present ...